Mini review
Chronic non-bacterial osteomyelitis (CNO) belongs to the growing spectrum of autoinflammatory diseases and primarily affects the skeletal system. Peak onset ranges between 7 and 12 years of age. The clinical s...
Molecular and Cellular Pediatrics 2017 4:7
Published on: 6 July 2017
Review
Precursor B acute lymphoblastic leukemia (BCP-ALL), the most common childhood malignancy, arises from an expansion of malignant B cell precursors in the bone marrow. Epidemiological studies suggest that infect...
Molecular and Cellular Pediatrics 2017 4:6
Published on: 16 May 2017
Meeting abstracts
Molecular and Cellular Pediatrics 2017 4(Suppl 1):5
Published on: 10 May 2017
This article is part of a Supplement: Volume 4 Supplement 1
Review
The intrauterine environment was long considered sterile. However, several infectious threats are already present during fetal life. This review focuses on the postnatal immunological consequences of prenatal ...
Molecular and Cellular Pediatrics 2017 4:4
Published on: 21 April 2017
Short Communication
Exposure to second-hand tobacco smoke (SHS) is one of the prime risk factors for chronic lung disease development. Smoking during pregnancy may lead to birth defects in the newborn that include pulmonary dysfu...
Molecular and Cellular Pediatrics 2017 4:3
Published on: 2 February 2017
Review
The developmental origin of health and disease concept identifies the brain, cardiovascular, liver, and kidney systems as targets of fetal adverse programming with adult consequences. As the limits of viabilit...
Molecular and Cellular Pediatrics 2017 4:2
Published on: 18 January 2017
Review
Cystic fibrosis (CF) is a genetic disease in which bacterial infections of the airways play a major role in the long-term clinical outcome. In recent years, a number of next-generation sequencing (NGS)-based s...
Molecular and Cellular Pediatrics 2017 4:1
Published on: 17 January 2017
Review
The pathological course of several chronic inflammatory diseases, including cystic fibrosis, chronic obstructive pulmonary disease, and rheumatoid arthritis, features an aberrant innate immune response dominat...
Molecular and Cellular Pediatrics 2016 3:38
Published on: 5 December 2016
Research
Rett syndrome is best known due to its severe and devastating symptoms in the central nervous system. It is produced by mutations affecting the Mecp2 gene that codes for a transcription factor. Nevertheless, evid...
Molecular and Cellular Pediatrics 2016 3:37
Published on: 21 November 2016
Research
Wilms’ tumor is an embryonal neoplasm of the kidney that accounts for approximately 6 % of all childhood tumors. The chemokine CXCL12 (C-X-C chemokine ligand 12) and its ligand CXCR4 (C-X-C chemokine receptor ...
Molecular and Cellular Pediatrics 2016 3:36
Published on: 10 November 2016
Mini review
Impaired cellular innate immune defense accounts for susceptibility to sepsis and its high morbidity and mortality in preterm infants. Leukocyte recruitment is an integral part of the cellular immune response ...
Molecular and Cellular Pediatrics 2016 3:35
Published on: 24 October 2016
Review
Bronchopulmonary dysplasia (BPD) is one of the most common chronic lung diseases in infants caused by pre- and/or postnatal lung injury. BPD is characterized by arrested alveolarization and vascularization due...
Molecular and Cellular Pediatrics 2016 3:34
Published on: 7 October 2016
Short Communication
Neonatal leukemia is a rare disease with an estimated prevalence of about one to five in a million neonates. The majority being acute myeloid leukemia (AML), neonatal leukemia can present with a variety of sym...
Molecular and Cellular Pediatrics 2016 3:30
Published on: 29 August 2016
Case Study
Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by self-limited recurrent attacks of fever and serositis. Patients may develop renal amyloidosis. Colchicine prevents attacks ...
Molecular and Cellular Pediatrics 2016 3:33
Published on: 15 August 2016
Editorial
Molecular and Cellular Pediatrics 2016 3:32
Published on: 12 August 2016
Mini review
Asthma is the most common chronic disease starting in childhood and persisting into adulthood in many cases. During childhood, different forms of asthma and wheezing disorders exist that can be discriminated b...
Molecular and Cellular Pediatrics 2016 3:31
Published on: 10 August 2016
Mini review
Influenza viruses (IVs) circulate seasonally and are a common cause of respiratory infections in pediatric and adult patients. Additionally, recurrent pandemics cause massive morbidity and mortality worldwide....
Molecular and Cellular Pediatrics 2016 3:29
Published on: 1 August 2016
Mini review
Retinoic acid (RA), the active form of vitamin A, regulates key developmental processes in multiple organs. In the developing lung, RA is crucial for normal growth and differentiation of airways. Disruption in...
Molecular and Cellular Pediatrics 2016 3:28
Published on: 1 August 2016
Mini review
Asthma represents the most common chronic childhood disease worldwide. Whereas preschool children present with wheezing triggered by different factors (multitrigger and viral wheeze), clinical asthma manifesta...
Molecular and Cellular Pediatrics 2016 3:27
Published on: 28 July 2016
Editorial
Molecular and Cellular Pediatrics 2016 3:26
Published on: 27 July 2016
Review
Chronic lung disease remains the major cause of morbidity and mortality in patients with cystic fibrosis (CF). Recent studies in young children with CF diagnosed by newborn screening identified neutrophil elas...
Molecular and Cellular Pediatrics 2016 3:25
Published on: 25 July 2016
Review
Chronic lung disease of the newborn, also known as bronchopulmonary dysplasia (BPD), is the most common chronic lung disease in early infancy and results in an increased risk for long-lasting pulmonary impairm...
Molecular and Cellular Pediatrics 2016 3:24
Published on: 12 July 2016
Mini review
Bronchopulmonary dysplasia is a chronic lung disease of preterm infants. It is caused by the disturbance of physiologic lung development mainly in the saccular stage with lifelong restrictions of pulmonary fun...
Molecular and Cellular Pediatrics 2016 3:23
Published on: 29 June 2016
Research
Neonatal lactic acidosis can be associated to severe inborn errors of metabolism. Rapid identification of the underlying disorder may improve the clinical management through reliable counseling of the parents ...
Molecular and Cellular Pediatrics 2016 3:22
Published on: 17 June 2016
Mini review
The gut mucosa is continuously exposed to food and microbial antigens. Both enterocytes and intraepithelial lymphocytes have a pivotal role in maintaining the integrity of intestinal mucosa, as these cells gua...
Molecular and Cellular Pediatrics 2016 3:20
Published on: 1 June 2016
