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  1. Meeting abstracts

    Abstracts of the 52nd Workshop for Pediatric Research

    Rhea van den Bruck, Patrick P. Weil, Thomas Ziegenhals, Philipp Schreiner, Stefan Juranek, Daniel Gödde, Silvia Vogel, Frauke Schuster, Valerie Orth, Johannes Dörner, Daniel Pembaur, Meike Röper, Stefan Störkel, Hubert Zirngibl, Stefan Wirth, Andreas C. W. Jenke…

    Molecular and Cellular Pediatrics 2017 4(Suppl 1):5

    Published on: 10 May 2017

    This article is part of a Supplement: Volume 4 Supplement 1

  2. Review

    Human perinatal immunity in physiological conditions and during infection

    The intrauterine environment was long considered sterile. However, several infectious threats are already present during fetal life. This review focuses on the postnatal immunological consequences of prenatal ...

    Gijs T. J. van Well, Leonie A. Daalderop, Tim Wolfs and Boris W. Kramer

    Molecular and Cellular Pediatrics 2017 4:4

    Published on: 21 April 2017

  3. Review

    Renal consequences of preterm birth

    The developmental origin of health and disease concept identifies the brain, cardiovascular, liver, and kidney systems as targets of fetal adverse programming with adult consequences. As the limits of viabilit...

    Amelie Stritzke, Sumesh Thomas, Harish Amin, Christoph Fusch and Abhay Lodha

    Molecular and Cellular Pediatrics 2017 4:2

    Published on: 18 January 2017

  4. Research

    Severe changes in colon epithelium in the Mecp2-null mouse model of Rett syndrome

    Rett syndrome is best known due to its severe and devastating symptoms in the central nervous system. It is produced by mutations affecting the Mecp2 gene that codes for a transcription factor. Nevertheless, evid...

    Pamela Millar-Büchner, Amber R. Philp, Noemí Gutierrez, Sandra Villanueva, Bredford Kerr and Carlos A. Flores

    Molecular and Cellular Pediatrics 2016 3:37

    Published on: 21 November 2016

  5. Research

    Wilms’ tumor susceptibility: possible involvement of FOXP3 and CXCL12 genes

    Wilms’ tumor is an embryonal neoplasm of the kidney that accounts for approximately 6 % of all childhood tumors. The chemokine CXCL12 (C-X-C chemokine ligand 12) and its ligand CXCR4 (C-X-C chemokine receptor ...

    Patricia Midori Murobushi Ozawa, Carolina Batista Ariza, Roberta Losi-Guembarovski, Alda Losi Guembarovski, Carlos Eduardo Coral de Oliveira, Bruna Karina Banin-Hirata, Marina Okuyama Kishima, Diego Lima Petenuci and Maria Angelica Ehara Watanabe

    Molecular and Cellular Pediatrics 2016 3:36

    Published on: 10 November 2016

  6. Mini review

    Leukocyte recruitment in preterm and term infants

    Impaired cellular innate immune defense accounts for susceptibility to sepsis and its high morbidity and mortality in preterm infants. Leukocyte recruitment is an integral part of the cellular immune response ...

    Katinka Karenberg, Hannes Hudalla and David Frommhold

    Molecular and Cellular Pediatrics 2016 3:35

    Published on: 24 October 2016

  7. Short Communication

    Transient spontaneous remission in congenital MLL-AF10 rearranged acute myeloid leukemia presenting with cardiorespiratory failure and meconium ileus

    Neonatal leukemia is a rare disease with an estimated prevalence of about one to five in a million neonates. The majority being acute myeloid leukemia (AML), neonatal leukemia can present with a variety of sym...

    Tobias Gyárfás, Juergen Wintgens, Wolfgang Biskup, Ilske Oschlies, Wolfram Klapper, Reiner Siebert, Susanne Bens, Claudia Haferlach, Roland Meisel, Michaela Kuhlen and Arndt Borkhardt

    Molecular and Cellular Pediatrics 2016 3:30

    Published on: 29 August 2016

  8. Mini review

    Early origins of asthma (and allergy)

    Asthma is the most common chronic disease starting in childhood and persisting into adulthood in many cases. During childhood, different forms of asthma and wheezing disorders exist that can be discriminated b...

    Michael Kabesch

    Molecular and Cellular Pediatrics 2016 3:31

    Published on: 10 August 2016

  9. Mini review

    Vitamin A-retinoid signaling in pulmonary development and disease

    Retinoic acid (RA), the active form of vitamin A, regulates key developmental processes in multiple organs. In the developing lung, RA is crucial for normal growth and differentiation of airways. Disruption in...

    Hector A. Marquez and Wellington V. Cardoso

    Molecular and Cellular Pediatrics 2016 3:28

    Published on: 1 August 2016

  10. Mini review

    The puzzle of immune phenotypes of childhood asthma

    Asthma represents the most common chronic childhood disease worldwide. Whereas preschool children present with wheezing triggered by different factors (multitrigger and viral wheeze), clinical asthma manifesta...

    Katja Landgraf-Rauf, Bettina Anselm and Bianca Schaub

    Molecular and Cellular Pediatrics 2016 3:27

    Published on: 28 July 2016

  11. Research

    Mendeliome sequencing enables differential diagnosis and treatment of neonatal lactic acidosis

    Neonatal lactic acidosis can be associated to severe inborn errors of metabolism. Rapid identification of the underlying disorder may improve the clinical management through reliable counseling of the parents ...

    Walid Fazeli, Mert Karakaya, Peter Herkenrath, Anne Vierzig, Jörg Dötsch, Jürgen-Christoph von Kleist-Retzow and Sebahattin Cirak

    Molecular and Cellular Pediatrics 2016 3:22

    Published on: 17 June 2016

  12. Mini review

    The cross-talk between enterocytes and intraepithelial lymphocytes

    The gut mucosa is continuously exposed to food and microbial antigens. Both enterocytes and intraepithelial lymphocytes have a pivotal role in maintaining the integrity of intestinal mucosa, as these cells gua...

    Serena Vitale, Stefania Picascia and Carmen Gianfrani

    Molecular and Cellular Pediatrics 2016 3:20

    Published on: 1 June 2016

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