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  1. Content type: Research

    Sodium channels predominantly expressed in brain are expressed in myocardial tissue and play an important role in cardiac physiology. Alterations of sodium channels are known to result in neurological disease ...

    Authors: Ulrich Krause, Christian Alflen, Michael Steinmetz, Matthias J Müller, Thomas Quentin and Thomas Paul

    Citation: Molecular and Cellular Pediatrics 2015 2:5

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  2. Content type: Research

    Term and near-term infants are at high risk of developing brain injury and life-long disability if they have suffered from severe perinatal asphyxia. We hypothesized that propofol administration to the materna...

    Authors: Matthias Seehase, Ward Jennekens, Alex Zwanenburg, Peter Andriessen, Jennifer JP Collins, Elke Kuypers, Luc J Zimmermann, Johan SH Vles, Antonio WD Gavilanes and Boris W Kramer

    Citation: Molecular and Cellular Pediatrics 2015 2:4

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  3. Content type: Review

    Chitin, after cellulose, the second most abundant biopolymer on earth, is a key component of insects, fungi, and house-dust mites. Lower life forms are endowed with chitinases to defend themselves against chit...

    Authors: Ines Mack, Andreas Hector, Marlene Ballbach, Julius Kohlhäufl, Katharina J Fuchs, Alexander Weber, Marcus A Mall and Dominik Hartl

    Citation: Molecular and Cellular Pediatrics 2015 2:3

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  4. Content type: Research

    MicroRNA (miRNA) and messenger RNA (mRNA) expression differs in cystic fibrosis (CF) versus non-CF bronchial epithelium. Here, the role of miRNA in basal regulation of the transcription factor ATF6 was investi...

    Authors: Irene K Oglesby, Raman Agrawal, Marcus A Mall, Noel G McElvaney and Catherine M Greene

    Citation: Molecular and Cellular Pediatrics 2015 2:1

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  5. Content type: Review

    Protein homeostasis describes the tight supervision of protein synthesis, correct protein maturation and folding, as well as the timely disposal of unwanted and damaged proteins by the ubiquitin-proteasome pat...

    Authors: Silke Meiners and Korbinian Ballweg

    Citation: Molecular and Cellular Pediatrics 2014 1:11

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  6. Content type: Review

    Therapeutic hypothermia is an effective cytoprotectant and promising intervention shown to improve outcome in patients following cardiac arrest and neonatal hypoxia-ischemia. However, despite our clinical and ...

    Authors: Katharina Rose Luise Schmitt, Giang Tong and Felix Berger

    Citation: Molecular and Cellular Pediatrics 2014 1:7

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  7. Content type: Mini review

    Matrix metalloproteinases are vital drivers of synaptic remodeling in health and disease. It is suggested that at early stages of epileptogenesis, inhibition of matrix metalloproteinases may help ameliorate ce...

    Authors: Chrysanthy Ikonomidou

    Citation: Molecular and Cellular Pediatrics 2014 1:6

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  8. Content type: Mini review

    Most cancer therapies are devised for adult or even elder patients. However, when dealing with pediatric cancers, additional considerations are needed.

    Authors: Mike-Andrew Westhoff, Oliver Brühl and Klaus-Michael Debatin

    Citation: Molecular and Cellular Pediatrics 2014 1:10

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  9. Content type: Mini review

    MicroRNAs (miRNAs) are crucial regulators of human immunity e.g. against Mycobacterium tuberculosis. Against the background of still alarming high mortality of tuberculosis effective biomarkers to improve diagnos...

    Authors: Bianca Ueberberg, Malte Kohns, Ertan Mayatepek and Marc Jacobsen

    Citation: Molecular and Cellular Pediatrics 2014 1:8

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  10. Content type: Research

    Deficiency of very long-chain acyl-CoA dehydrogenase (VLCAD) is the most common disorder of mitochondrial β-oxidation of long-chain fatty acids. In order to maintain glucose homeostasis, the kidney and liver a...

    Authors: Sara Tucci, Antonia Krogmann, Diran Herebian and Ute Spiekerkoetter

    Citation: Molecular and Cellular Pediatrics 2014 1:5

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  11. Content type: Meeting abstract

    Authors: Jan Marquard, Silke Otter, Alena Welters, Diran Herebian, Fatih Demir, Annett Schroeter, Olaf Kletke, Martin Kragl, Daniel Eberhard, Barbara Bartosinska, Masa Skelin Klemen, Andraz Stozer, Martin Köhler, Alin Stirban, Freimut Schliess, Tim Heise…

    Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A26

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    This article is part of a Supplement: Volume 1 Supplement 1

  12. Content type: Meeting abstract

    Authors: Henner Morbach, Greta Meyers, Yen-Shing Ng, Jean-Nicolas Schickel, Laurence Menard, Sergei Rudchenko, Jessica L Rojas, Charlotte Cunningham-Rundles, Mary Ellen Conley, Ismail Reisli, Jose Luis Franco and Eric Meffre

    Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A16

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    This article is part of a Supplement: Volume 1 Supplement 1

  13. Content type: Meeting abstract

    Authors: Maren Leifheit-Nestler, Robert Große Siemer, Kathrin Flasbart, Dagmar-Christiane Fischer, Michael Klintschar, Jan U Becker, Christoph Aufricht, Tomas Seeman and Dieter Haffner

    Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A25

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    This article is part of a Supplement: Volume 1 Supplement 1

  14. Content type: Mini review

    Fragile X is the most common form of inherited intellectual disability and the leading known genetic cause of autism. There is currently no cure or approved medication for fragile X although various drugs targ...

    Authors: Cara J Westmark

    Citation: Molecular and Cellular Pediatrics 2014 1:1

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  15. Content type: Review

    Congenital leptin deficiency is a rare autosomal recessive monogenic obesity syndrome caused by mutations in the leptin gene. This review describes the molecular and cellular characteristics of the eight disti...

    Authors: Jan-Bernd Funcke, Julia von Schnurbein, Belinda Lennerz, Georgia Lahr, Klaus-Michael Debatin, Pamela Fischer-Posovszky and Martin Wabitsch

    Citation: Molecular and Cellular Pediatrics 2014 1:3

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