Citation: Molecular and Cellular Pediatrics 2015 2(Suppl 1):A23
Articles
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Citation: Molecular and Cellular Pediatrics 2015 2(Suppl 1):A15
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Ciliopathies - from rare inherited cystic kidney diseases to basic cellular function
Primary cilia are membrane-bound microtubule-based protuberances of the cell membrane projecting to the extracellular environment. While little attention was paid to this subcellular structure over a long time...
Citation: Molecular and Cellular Pediatrics 2015 2:8
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Submicroscopic copy-number variations associated with 46,XY disorders of sex development
Mutations in known causative genes and cytogenetically detectable chromosomal rearrangements account for a fraction of cases with 46,XY disorders of sex development (DSD). Recent advances in molecular cytogene...
Citation: Molecular and Cellular Pediatrics 2015 2:7
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Metabolic origins of childhood asthma
Childhood obesity and incidence of asthma are increasing globally. The parallel increase of the two suggests that obesity and asthma may be related and that abnormalities in the lipid and/or glucose metabolism...
Citation: Molecular and Cellular Pediatrics 2015 2:6
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Characterization of maturation of neuronal voltage-gated sodium channels SCN1A and SCN8A in rat myocardium
Sodium channels predominantly expressed in brain are expressed in myocardial tissue and play an important role in cardiac physiology. Alterations of sodium channels are known to result in neurological disease ...
Citation: Molecular and Cellular Pediatrics 2015 2:5
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Propofol administration to the maternal-fetal unit improved fetal EEG and influenced cerebral apoptotic pathway in preterm lambs suffering from severe asphyxia
Term and near-term infants are at high risk of developing brain injury and life-long disability if they have suffered from severe perinatal asphyxia. We hypothesized that propofol administration to the materna...
Citation: Molecular and Cellular Pediatrics 2015 2:4
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The role of chitin, chitinases, and chitinase-like proteins in pediatric lung diseases
Chitin, after cellulose, the second most abundant biopolymer on earth, is a key component of insects, fungi, and house-dust mites. Lower life forms are endowed with chitinases to defend themselves against chit...
Citation: Molecular and Cellular Pediatrics 2015 2:3
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Bronchopulmonary dysplasia - an overview about pathophysiologic concepts
Neonatal chronic lung disease in the preterm infant, i.e. bronchopulmonary dysplasia (BPD) is characterized by impaired pulmonary development with its effects persisting into adulthood. Triggered in the immatu...
Citation: Molecular and Cellular Pediatrics 2015 2:2
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miRNA-221 is elevated in cystic fibrosis airway epithelial cells and regulates expression of ATF6
MicroRNA (miRNA) and messenger RNA (mRNA) expression differs in cystic fibrosis (CF) versus non-CF bronchial epithelium. Here, the role of miRNA in basal regulation of the transcription factor ATF6 was investi...
Citation: Molecular and Cellular Pediatrics 2015 2:1
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Proteostasis in pediatric pulmonary pathology
Protein homeostasis describes the tight supervision of protein synthesis, correct protein maturation and folding, as well as the timely disposal of unwanted and damaged proteins by the ubiquitin-proteasome pat...
Citation: Molecular and Cellular Pediatrics 2014 1:11
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Mechanisms of hypothermia-induced cell protection in the brain
Therapeutic hypothermia is an effective cytoprotectant and promising intervention shown to improve outcome in patients following cardiac arrest and neonatal hypoxia-ischemia. However, despite our clinical and ...
Citation: Molecular and Cellular Pediatrics 2014 1:7
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Matrix metalloproteinases and epileptogenesis
Matrix metalloproteinases are vital drivers of synaptic remodeling in health and disease. It is suggested that at early stages of epileptogenesis, inhibition of matrix metalloproteinases may help ameliorate ce...
Citation: Molecular and Cellular Pediatrics 2014 1:6
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Fanconi anemia: young patients at high risk for squamous cell carcinoma
Fanconi anemia is one of the best studied inherited cancer-prone diseases. Greatly improved protocols for hematopoietic stem cell transplantation increasingly save the lives of these young patients. However, i...
Citation: Molecular and Cellular Pediatrics 2014 1:9
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Cancer therapy: know your enemy?
Most cancer therapies are devised for adult or even elder patients. However, when dealing with pediatric cancers, additional considerations are needed.
Citation: Molecular and Cellular Pediatrics 2014 1:10
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Are microRNAs suitable biomarkers of immunity to tuberculosis?
MicroRNAs (miRNAs) are crucial regulators of human immunity e.g. against Mycobacterium tuberculosis. Against the background of still alarming high mortality of tuberculosis effective biomarkers to improve diagnos...
Citation: Molecular and Cellular Pediatrics 2014 1:8
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Renal response to short- and long-term exercise in very-long-chain acyl-CoA dehydrogenase-deficient (VLCAD−/−) mice
Deficiency of very long-chain acyl-CoA dehydrogenase (VLCAD) is the most common disorder of mitochondrial β-oxidation of long-chain fatty acids. In order to maintain glucose homeostasis, the kidney and liver a...
Citation: Molecular and Cellular Pediatrics 2014 1:5
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A29
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A28
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A27
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A26
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A25
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A24
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A23
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A22
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A21
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A20
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A19
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A18
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A17
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A16
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A15
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A14
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A13
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A12
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A11
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A10
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A9
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A8
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A7
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A6
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A5
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A4
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A3
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A2
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Citation: Molecular and Cellular Pediatrics 2014 1(Suppl 1):A1
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Molecular and Cellular Pediatrics
No abstract.
Citation: Molecular and Cellular Pediatrics 2014 1:4
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Monogenic forms of childhood obesity due to mutations in the leptin gene
Congenital leptin deficiency is a rare autosomal recessive monogenic obesity syndrome caused by mutations in the leptin gene. This review describes the molecular and cellular characteristics of the eight disti...
Citation: Molecular and Cellular Pediatrics 2014 1:3
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Perinatal programming - myths, fact, and future of research
Perinatal programming, i.e., the (epigenetic) modification of (genetic) functions throughout lifetime, suffers from the notion of premature theories and difficult and extensive research strategies.
Citation: Molecular and Cellular Pediatrics 2014 1:2
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The quest for fragile X biomarkers
Fragile X is the most common form of inherited intellectual disability and the leading known genetic cause of autism. There is currently no cure or approved medication for fragile X although various drugs targ...
Citation: Molecular and Cellular Pediatrics 2014 1:1
- ISSN: 2194-7791 (electronic)