Articles

Microevolution of Pseudomonas aeruginosa in cystic fibrosis lungs

Authors: Nina Cramer, Jens Klockgether, Colin F Davenport and Burkhard Tümmler

NMDA receptor dependent anti-diabetic effects

Authors: Jan Marquard, Silke Otter, Alena Welters, Diran Herebian, Fatih Demir, Annett Schroeter, Olaf Kletke, Martin Kragl, Daniel Eberhard, Barbara Bartosinska, Masa Skelin Klemen, Andraz Stozer, Martin Köhler, Alin Stirban, Freimut Schliess, Tim Heise…

A novel mutation in the PAX8 promoter region causes permanent congenital hypothyroidism in a patient with Down’s Syndrome

Authors: Pia Hermanns, Sunia Khadouma, Scott Shepherd, Mohamed Mansor, John Schulga, J Jones, M Donaldson and Joachim Pohlenz

Overcoming apoptosis resistance in high risk acute lymphoblastic leukemia by SMAC mimetics in a preclinical ALL xenograft model in vivo

Authors: Melanie Schirmer, Manon Queudeville, Luca Trentin, Sarah Mirjam Eckhoff, Lüder Hinrich Meyer and Klaus-Michael Debatin

Characterization of oncogenes on chromosome 21 identified by shRNA-based viability screening

Authors: Lena Stachorski, Veera Raghavan Thangapandi, Dirk Reinhardt and Jan-Henning Klusmann

The accumulation of multifunctional T cells in hypertrophied adenoids is dependent on age and related to clinical manifestation

Authors: J Knolle, K Hebel, C Arens, C Hahne, G Jorch and M Brunner-Weinzierl

Molecular dissection of human B-cell tolerance – insights from patients with rare genetic diseases

Authors: Henner Morbach, Greta Meyers, Yen-Shing Ng, Jean-Nicolas Schickel, Laurence Menard, Sergei Rudchenko, Jessica L Rojas, Charlotte Cunningham-Rundles, Mary Ellen Conley, Ismail Reisli, Jose Luis Franco and Eric Meffre

Alternating hemiplegia of childhood and rapid-onset dystonia-parkinsonism are both ATP1A3-related disorders

Authors: Hendrik Rosewich, Holger Thiele, Andreas Ohlenbusch, Ulrike Maschke, Peter Frommolt, Peter Nürnberg, Knut Brockmann and Jutta Gärtner

Uncovering common pathogenic transcriptional dysregulations in Silver-Russell syndrome

Authors: Florian Bohne, Ursula Martiné, Matthias Begemann, Thomas Eggermann, Thorsten Enklaar and Dirk Prawitt

Connexin 37 and Connexin 43 genotypes in correlation to cytokines in induced sputum and blood in cystic fibrosis (CF)

Authors: M Ludwig, O Eickmeier, C Smaczny, F Schreiner, W Dubois, D NGampolo, R Schubert, S Zielen, R Ganschow and S Schmitt-Grohé

MIRIS – an adequate method to measure fortified breast milk?

Authors: Alexandra Kreissl, Valentina Zwiauer, Andreas Repa, Christoph Binder, Margarita Thanhaeuser, Angelika Berger and Nadja Haiden

Neuroprotective effects of hypothermia and levetiracetam after hypoxia-ischemia in the neonatal mouse brain

Authors: Katja Straßer, Daniela Brait, Laura Lückemann, Barbara Simone Reinboth, Josephine Herz, Ivo Bendix and Ursula Felderhoff-Müser

Fetal growth pattern is regulated sex-specific dependent on maternal BMI

Authors: B Brune, D Naehter and T Brune

Genetic risk factors for respiratory diseases of preterm infants

Authors: Friederike Pagel, Sarah Leick, Michael Preuß, Christoph Härtel, Egbert Herting and Wolfgang Göpel

Molecular and Cellular Pediatrics

No abstract.

Authors: Klaus-Michael Debatin

Monogenic forms of childhood obesity due to mutations in the leptin gene

Congenital leptin deficiency is a rare autosomal recessive monogenic obesity syndrome caused by mutations in the leptin gene. This review describes the molecular and cellular characteristics of the eight disti...

Authors: Jan-Bernd Funcke, Julia von Schnurbein, Belinda Lennerz, Georgia Lahr, Klaus-Michael Debatin, Pamela Fischer-Posovszky and Martin Wabitsch

Perinatal programming - myths, fact, and future of research

Perinatal programming, i.e., the (epigenetic) modification of (genetic) functions throughout lifetime, suffers from the notion of premature theories and difficult and extensive research strategies.

Authors: Jörg Dötsch

The quest for fragile X biomarkers

Fragile X is the most common form of inherited intellectual disability and the leading known genetic cause of autism. There is currently no cure or approved medication for fragile X although various drugs targ...

Authors: Cara J Westmark