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Table 2 Characteristics of hospitalized patients

From: Adverse effects of remdesivir for the treatment of acute COVID-19 in the pediatric population: a retrospective observational study

Overall characteristics (n = 65)

Number, %

Baseline oxygen requirement

 

 Room air

29 (45)

 Low flow

32 (49)

 High flow

4 (6)

Presence of co-viral infection

12 (18)

Median duration of hospital admission (days)

 

 Overall cohort

4 (IQR 3–5 days; range 1–48 days)

 Patients with ≥ 3 comorbidities

5 (IQR 4–7 days; range 2–23 days)

Median duration of symptom onset to start of RDV (days)

3 (IQR 2–5 days; range 0–15 days)

Required PICU admission

16 (25)

Highest level of oxygen required

 

 Room air

22 (34)

 Low flow

21 (32)

 High flow

18 (28)

 Mechanical ventilation

4 (6)

Median duration of oxygen support after start of RDV (days)

2 (IQR 1–5 days; range 1–44 days)

Median duration of RDV treatment (days)

2

Duration of RDV therapy (days)

 

 1

2 (3)

 2

10 (15)

 3

26 (40)

 4

8 (12)

 5

19 (30)

Concomitant SARS-CoV-2 therapies received

 

 Anticoagulation

37 (57)

 Corticosteroids

53 (82)

 Antibiotics

25 (38)

 Baricitinib

6 (9)

 Anakinra

1 (2)

Mild/moderate COVID-19, high-risk for severe disease (n = 22)

Number, %

Duration of RDV treatment (days)

 

 2

2 (9)

 3

15 (68)

 4

0 (0)

 5

5 (23)

Highest level of oxygen required

 

 Room air

20 (91)

 Low flow

2 (9)

  1. RDV remdesivir, IQR interquartile range, PICU pediatric intensive care unit