Fig. 5
From: Installation of the developing nephron in the fetal human kidney during advanced pregnancy
View onto the installation of the mature renal vesicle (mRV) in the fetal human kidney during advanced pregnancy by the optical microscope. While the mature renal vesicle arises, the local installation supports at its distal pole (DP) a partial separation (flash) from the overlying pretubular aggregate (PTA). This is visible at the end of the clear interface (black asterisks) and the adhesion (white asterisks). It is near the section border between the head (H) and conus (CO) of the CD ampulla (A). Underneath, the adhesion is replaced by a close interstitial cleft (white circle). During the further development, the medial aspect of the mature renal vesicle elongates in parallel with the upper conus of the CD ampulla. The lateral part of the distal pole at the mature renal vesicle remains connected with the proximal end of the PTA via a two-layered progenitor cell strand (white arrow head). C renal capsule, + lumen, PRA perforating radiate artery