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Table 1 Characteristics of the patients with available serum samples

From: A novel serum calprotectin (MRP8/14) particle-enhanced immuno-turbidimetric assay (sCAL turbo) helps to differentiate systemic juvenile idiopathic arthritis from other diseases in routine clinical laboratory settings

 

SJIA

Infections

SIDs

nsJIA

ALL

Controls

Samples, n

99

51

126

169

147

23

Age

6.8 (0.6–16.5)

4.5 (0.3–16.9)

5.5 (0.4–17.7)

6.4 (0.2–15.8)

4.4 (0.5–18.8)

13.2 (4.8–16.9)

Sex, f/m (% female)

45/49 (45)

31/20 (61)

60/66 (48)

114/55 (67)

67/75 (46)

11/12 (48)

WBC, cells/µl

14,700§ (3700–40,900)

11,375 (3400–38,000)

9520 (1100–25,000)

9560 (6700–22,100)

8700 (300–726,000)

n.d

ESR, mm/h

83 (4–170)

65 (5–109)

27# (1–140)

10## (1–104)

61 (9–160)

n.d

CRP, mg/dl

9.5* (1.2–41.2)

8.0** (1.2–44.1)

4.3 (1.0–32.8)

3.8 (0.1–8.9)

2.0 (0.8–18.5)

 < 0.5

  1. All data expressed as median (range) except otherwise stated
  2. WBC White blood cells, ESR Erythrocyte sedimentation rate, CRP C-reactive protein, n.d Not determined
  3. §WBC count significantly higher in SJIA compared to SIDs (p < 0.001) and ALL (p = 0.005)
  4. #ESR significantly lower in SIDs compared to SJIA (p < 0.001), infections (p < 0.01), and ALL (p < 0.001)
  5. ##ESR significantly lower in nsJIA compared all other disease groups (p < 0.001)
  6. *CRP significantly higher in SJIA compared to SIDs, nsJIA, and ALL (p < 0.001 for all)
  7. **CRP significantly higher in infections compared to ALL (p < 0.001)