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Molecular and Cellular Pediatrics
Fig. 4 | Molecular and Cellular Pediatrics

Fig. 4

From: A novel serum calprotectin (MRP8/14) particle-enhanced immuno-turbidimetric assay (sCAL turbo) helps to differentiate systemic juvenile idiopathic arthritis from other diseases in routine clinical laboratory settings

Fig. 4

ROC curves of routine inflammatory marker analyses. ROC analyses were performed to determine the overall accuracy of CRP, ESR, and WBC measurements in differentiating the major differential diagnoses in FUO, i.e., SJIA versus infections and leukemia. The ROC curves show analyses for A CRP in SJIA vs infections (AUC = 0.577, p = 0.134), B CRP in SJIA vs ALL (AUC = 0.831, p < 0.001), C CRP in SJIA vs SIDs (AUC = 0.702, p < 0.001), D ESR in SJIA vs infections (AUC = 0.658, p = 0.007), E ESR in SJIA vs ALL (0.547, p = 0.353), F ESR in SJIA vs SIDs (AUC = 0.789, p < 0.001), G WBCs in SJIA vs infections (AUC = 0.656, p = 0.003), H WBCs in SJIA vs ALL (AUC = 0.575, p = 0.056), I WBCs in SJIA vs SIDs (AUC = 0.741, p < 0.001). FUO, fever of unknown origin; SID, systemic inflammatory diseases

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