Sex differences in long-term kidney fibrosis following neonatal nephron loss during ongoing nephrogenesis

Molecular and Cellular Pediatrics

Table 3 Markers of renal development and integrity

	Male Co	Male UNX	Female Co	Female UNX
Wt-1 expression [fold change]	1.00 ± 0.07	0.70 ± 0.06 *	1.68 ± 0.10 ^§	1.08 ± 0.10 *^§
Nephrin expression [fold change]	1.00 ± 0.07	0.71 ± 0.07 *	1.60 ± 0.04 ^§	1.25 ± 0.116 *^§
Synaptopodin expression [fold change]	1.00 ± 0.08	1.04 ± 0.16	1.69 ± 0.08 ^§	1.49 ± 0.12 ^§
Gdnf epxression [fold change]	1.00 ± 0.11	0.68 ± 0.09	1.94 ± 0.16 ^§	1.21 ± 0.16 *^§
Itga8 expression [fold change]	1.00 ± 0.04	1.00 ± 0.09	1.93 ± 0.09 ^§	1.84 ± 0.29 ^§

UNX rat uninephrectomized at day 1 of life, Co age-matched sham-operated control
^*p < 0.05 versus respective control
^§p < 0.05 versus male