Table 2 Markers of renal inflammation and fibrosis

Mcp-1 expression [fold change]

1.00 ± 0.14

1.61 ± 0.55

0.91 ± 0.15

2.82 ± 1.04 *

Opn expression [fold change]

1.00 ± 0.20

8.23 ± 2.82 *

1.59 ± 0.35

8.57 ± 3.26 *

M1 macrophages [No./MPF]

2.51 ± 0.53

6.25 ± 1.47 *

2.73 ± 0.24

5.05 ± 1.17

M2 macrophages [No./40 MPFs]

16.63 ± 5.42

13.00 ± 1.36

27–55 ± 6.43

35.25 ± 14.69

Collagen I stain [% positive area]

0.77 ± 0.11

1.94 ± 0.26 *

0.76 ± 0.06

0.87 ± 0.14 ^§

Collagen I expression [fold change]

1.00 ± 0.10

2.70 ± 0.76 *

1.68 ± 0.16

3.05 ± 0.54 *

Collagen IV expression [fold change]

1.00 ± 0.06

1.69 ± 0.53

3.06 ± 0,50 ^§

2.90 ± 0.59