Table 1 Auxologic data and parameters of renal structure and function

Body weight [g]

761.21 ± 22.57

743.01 ± 27.61

404.58 ± 13.84 ^§

372.46 ± 30.4 ^§

Right kidney weight [g]

1.90 ± 0.07

3.49 ± 0.22 *

1.25 ± 0.05 ^§

2.05 ± 0.08 *^§

Glomerular perimeter [µm]

362.1 ± 7.5

413.0 ± 5.7 *

310.9 ± 7.4 ^§

364.1 ± 7.5 *^§

Mean arterial pressure [mmHg]

118.8 ± 2.1

122.1 ± 4.2

110.73 ± 1.12

108.82 ± 2.65 ^§

Serum creatinine [mg/dl]

0.31 ± 0.02

0.36 ± 0.02

0.26 ± 0.01 ^§

0.25 ± 0.02 ^§

Serum urea [mg/dl]

33.98 ± 1.57

38.73 ± 2.41

31.87 ± 1.26

29.76 ± 2.87 ^§

Serum phosphate [mmol/l]

1.93 ± 0.12

1.99 ± 0.16

1.26 ± 0.07 ^§

1.17 ± 0.06 ^§

Proteinuria [mg/d]

37.78 ± 14.37

209.11 ± 52.47 *

92.21 ± 38.67

387.38 ± 132.09 *

Kim-1 expression [fold change]

1.00 ± 0.32

4.48 ± 0.95

0.76 ± 0.31

7.76 ± 3.68 *

Ngal expression [fold change]

1.00 ± 0.11

4.20 ± 1.13

1.97 ± 0.38

10.42 ± 4.44 *^§