Table 1 American College of Rheumatology case definitions for neuropsychiatric SLE (1999) [21]

Central nervous system (CNS)

 Diffuse

Acute confusional state

Anxiety disorder

Aseptic meningitis

Cognitive dysfunction

Demyelinating syndrome (Fig. 1A)

Headache

Mood disorder

Psychosis

 Focal

Cerebrovascular disease (Fig. 2)

Movement disorder

Myelopathy (Fig. 1B)

Seizures

Peripheral nervous system (PNS)

 Acute inflammatory demyelinating polyradiculoneuropathy (Guillain-Barré syndrome) (Fig. 1C)

 Autonomic disorder

 Cranial neuropathy

 Mononeuropathy

 Myasthenia gravis

 Plexopathy

 Polyneuropathy