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Molecular and Cellular Pediatrics

Table 3 Aminoglycoside resistance gene profiles of the GNB in Iran

From: Evaluation of phenotypic and genotypic patterns of aminoglycoside resistance in the Gram-negative bacteria isolates collected from pediatric and general hospitals

AME genes

Acinetobacter spp. (327)

N (%)

E. coli (144)

N (%)

K. pneumoniae (140)

N (%)

P. aeruginosa (136)

N (%)

Enterobacter spp. (89)

N (%)

aac (6')-Ib + aph (3')-Ia + aadA15 + aph (3')-II + aph (3')-VIe (n = 14)

–

–

1/140 (0.7%)

8/136 (5.9%)

5/89 (5.6%)

aac (6')-Ib + aph (6) + aadA15 + aph (3')-II + aph (3')-Ia (n = 1)

–

1/144 (0.7%)

–

–

–

aac (6')-Ib + aph (3')-Ia + aadA15 + aph (3')-VIe (n = 52)

27/327 (8.2%)

5/144 (3.5%)

7/140 (5%)

3/136 (2.2%)

10/89 (11.2%)

aac (6')-Ib + aph (3')-Ia + aph (3')-II + aph (3')-VIe (n = 41)

9/327 (2.7%)

1/144 (0.7%)

7/140 (5%)

2/136 (1.5%)

22/89 (24.7%)

aph (3')-Ia + aph (3')-II + aac (6')-Ib + aph (6) (n = 29)

4/327 (1.2%)

1/144 (0.7%)

2/140 (1.4%)

–

22/89 (24.7%)

aac (6')-Ib + aadA15 + aph (3')-Ia + aph (6) (n = 6)

–

6/144 (4.2%)

–

–

–

aac (6')-Ib + aph (6) + aadA15 + aph (3')-VIe (n = 3)

–

3/144 (2%)

–

–

–

aac (6')-Ib + aph (3')-VIe (n = 57)

11/327 (3.4%)

10/144 (6.9%)

19/140 (13.6%)

11/136 (8%)

6/89 (6.7%)

aadA15 + aac (6')-Ib + aph (3')-VIe (n = 66)

24 (7.3%)

11/144 (7.6%)

25/140 (17.8%)

5/136 (3.7%)

1 (1.1%)

aph (3')-Ia + aadA15 + aac (6')-Ib (n = 25)

10/327 (3%)

7/144 (4.9%)

7/140 (5%)

–

1/89 (1.1%)

aac (6')-Ib + aph (6) + aph (3')-VIe (n = 12)

6/327 (1.8%)

–

–

5/136 (3.7%)

1/89 (1.1%)

aac (6')-Ib + aph (6) + aph (3')-II (n = 1)

1/327 (0.3%)

–

–

–

–

aac (6')-Ib + aadA15 (n = 37)

4/327 (1.2%)

14/144 (9.7%)

15/140 (10.7%)

2/136 (1.5%)

2/89 (2.2)

aph (3')-Ia + aadA15 (n = 15)

9/327 (2.7%)

4/144 (2.8%)

1/140 (0.7%)

–

1/89 (1.1%)

aac (6')-Ib + aph (6) (n = 3)

–

3/144 (2%)

–

–

–

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