Table 1 Endocrine investigations for monitoring children with isolated GHD
From: Evolving pituitary hormone deficits in primarily isolated GHD: a review and experts’ consensus
Pituitary hormone | Baseline investigation | Second-line investigation |
|---|---|---|
TSH | fT4, TSH | Not needed |
ACTH | Morning cortisol (7–9 am) | Synacthen test, insulin-hypoglycemia test |
LH/FSH | Inhibin B, LH, FSH, testosterone/estradiol | GnRH agonist test |
ADH | Early morning serum/urine osmolality | Water deprivation test, desmopressin test |