Fig. 2

Four-month old male infant with hepatosplenomegaly and cholestasis. Following sonography and elastography biopsy indicated. The result showed Niemann-Pick disease type A associated with liver fibrosis and reduced synthetic capacity of the liver. A B-mode imaging of the liver in the midclavicular line corresponding to hepatomegaly (Sequoia, Siemens, 5C3 probe). B SWE measurement in the right liver lobe. Shear wave speed of 2.82 m/s is significantly increased and has to be assessed in terms of fibrosis (Sequoia, Siemens, 5C1 probe)