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Molecular and Cellular Pediatrics
Fig. 7 | Molecular and Cellular Pediatrics

Fig. 7

From: The mutual patterning between the developing nephron and its covering tissues—valid reasons to rethink the search for traces left by impaired nephrogenesis

Fig. 7

Merging of the graphical sketches 3 to 6 demonstrates the mutual changes between the developing nephron and its covering tissues in the fetal human kidney during late gestation. Depicted are the a nephrogenic niche and pretubular aggregate (PTA), b the mesenchymal to epithelial transition, and c primitive renal vesicle (RV). In addition, the d mature, e extending, f extended renal vesicle, the g early, h mid, and i late comma-shaped body (CSB) and the j early, k mid, and l late S-shaped body (SSB) are shown. The sequence of sketches illustrates that not only the stages of nephron anlage, but also the covering tissues and the interjacent interstitium are changing. Renal capsule (C), collecting duct (CD) tubule, CD ampulla (A), perforating radiate artery (PRA, short black arrow), and lumen of the arising nephron + 

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