Fig. 2From: The mutual patterning between the developing nephron and its covering tissues—valid reasons to rethink the search for traces left by impaired nephrogenesisGraphical sketches depicting the translocation of the developing nephron in a nephrogenic compartment of the fetal human kidney during late gestation. In the district of progenitor cell recruitment (light) the a nephrogenic niche (black asterisk) with the pretubular aggregate (PTA), b the mesenchymal to epithelial transition, and c the primitive renal vesicle (RV) are visible. In the underlying area of nephron shaping (dark), the d mature, e extending, f extended renal vesicles, the g early, h mid, and i late comma-shaped body (CSB) and the j early, k mid, and l late S-shaped body (SSB) are registered. While the district of progenitor cell recruitment maintains a constant size, the area of nephron shaping continues to expand during the formation of c the matured renal vesicle (15 × 20 µm) to l the late S-shaped body (100 × 100 µm). Renal capsule (C), collecting duct (CD) tubule, CD ampulla (A), perforating radiate artery (PRA, short black arrow), and lumen of the arising nephron + Back to article page