Fig. 3

Timeline of detection and subsequent regression of different tumor manifestations in our patient. Thickness of bars qualitatively represents size of tumor lesions, with the paraspinal index tumor being the largest one (Ø 3 cm). After intestinal polyposis was detected, VAC chemotherapy was applied. All other manifestations were asymptomatic and thus managed by a watch-and-wait strategy. All tumor lesions showed continuous regression throughout the second year of life, as shown by decreasing thickness of bars. Please note that last whole body MRI at the age of 17 months revealed a small residual mass of the initial paraspinal tumor, and last MRI of the head at the age of 41 months also showed residual changes near the confluens sinuum, so these two lesions had not completely disappeared to the date of last MRI