Table 3 Clinical and laboratory findings at the time of diagnosis
Patient 1 | Patient 2 | Reference range | ||
|---|---|---|---|---|
Age | 20 years | 29 years | ||
Weight | kg | 172 | 120.5 | |
Height | m | 1.66 | 1.70 | |
BMI | kg/m2 | 62.1 | 41.6 | |
BMI SDS | 3.64 | 3.07 | ||
Blood pressure | mmHG | 121/85 | 137/86 | |
Pubertal stage by Tanner | PH, 5; B, 5 | PH, 6; testicular volume, 16 ml and 14 ml | ||
Insulin-like growth factor 1 | ng/ml | 231 | 182 | f, 122–384; m, 117–321 |
Leptin | μg/l | 34.4 | 12.5 | 3.6–11.1 |
Total cholesterol | mmol/l | 4.3 | 3.8 | < 5.0 |
LDL cholesterol | mmol/l | 3.2 | 2.3 | > 1.0 |
HDL cholesterol | mmol/l | 0.5 | 1.2 | < 3.0 |
Thyreotropin | MIU/l | 2.02 | 1.88 | 12.8–20.4 |
Free thyroxine | pmol/l | 11.7 | 19 | 3.13–6.76 |
Testosterone | μg/l | 0.19 | 4.25 | f, 0.084–0.481; m, 2.490–8.360 |