Table 6 Effect of selected pregnancy concurrent events on cytochromes metabolic activity
Offspring gender (n = 98) | Pregnancy associated hypertension | Prenatal steroids | |||||||
|---|---|---|---|---|---|---|---|---|---|
Cytochrome metabolic activity | Male (n = 54) | Female (n = 44) | p | Exposed (n = 10) | Unexposed (n = 80) | p | Exposed (n = 68) | Unexposed (n = 22) | p |
CYP1A2 a | 0.05 (0.02–0.16) | 0.09 (0.02–0.26) | NS | 0.08 (0.02–0.37) | 0.05 (0.01–0.18) | NS | 0.04 (0.01–0.11) | 0.13 (0.03–0.32) | † 0.03 |
CYP2E1 b | 0.35 (0.02–1.24) | 0.45 (0.04–1.24) | NS | 1.61 (0.66–1.94) | 0.37 (0.02–1.12) | † 0.02 | 0.46 (0.02–1.79) | 0.37 (0.05–0.45) | NS |
CYP2E1 c | 0.04 (0.02–0.11) | 0.09 (0.03–0.21) | † 0.03 | 0.08 (0.02–0.42) | 0.07 (0.02–0.15) | NS | 0.05 (0.02–0.15) | 0.09 (0.02–0.21) | NS |