Table 5 Effect of selected environmental factors on cytochromes metabolic activity
Charbroiled meat | Charcoal fumes | Acetaminophen | |||||||
|---|---|---|---|---|---|---|---|---|---|
Cytochrome metabolic activity | Exposed (n = 46) | Unexposed (n = 44) | p | Exposed (n = 5) | Unexposed (n = 85) | p | Exposed (n = 6) | Unexposed (n = 84) | p |
CYP1A2 a | 0.11 (0.02–0.30) | 0.05 (0.01–0.16) | NS | 0.13 (0.05–0.13) | 0.05 (0.02–0.18) | NS | 0.05 (0.02–0.09) | 0.05 (0.02–0.18) | NS |
CYP2E1 b | 0.52 (0.18–1.80) | 0.26 (0.01–0.81) | † 0.02 | 0.40 (0.39–1.79) | 0.40 (0.02–1.25) | NS | 2.0 (1.24–4.46) | 0.39 (0.02–1.13) | † 0.02 |
CYP2E1 c | 0.09 (0.02–0.20) | 0.05 (0.01–0.15) | NS | 0.08 (0.08–0.15) | 0.07 (0.02–0.16) | NS | 0.12 (0.04–0.20) | 0.07 (0.02–0.15) | NS |