Molecular and Cellular Pediatrics

Table 4 Comparative analysis of allelic frequencies of polymorphisms of CYP1A2 and CYP2E1 with other populations

From: Modulation of CYP2E1 metabolic activity in a cohort of confirmed caffeine ingesting pregnant women with preterm offspring

	CYP1A21F* rs762551			CYP2E15A* rs3813867			CYP2E15B* rs2031920
Population	A	C	p †	G	C	p †	C	T	p †
AFR	0.562	0.438	< 0.0001	0.933	0.067	< 0.0001	0.998	0.002	< 0.0001
AMR	0.758	0.242	0.303	0.878	0.122	0.0073	0.885	0.115	0.0248
EAS	0.673	0.327	0.002	0.798	0.202	0.0375	0.798	0.202	0.0027
EUR	0.680	0.320	0.006	0.959	0.041	< 0.0001	0.959	0.041	< 0.0001
SAS	0.535	0.465	< 0.0001	0.991	0.009	< 0.0001	0.991	0.009	< 0.0001
NEM	0.737	0.263	Ref	0.835	0.165	Ref	0.850	0.150	Ref

(1000 Genomes Project Consortium et al., [23]) †Fisher´s exact test. AFR African, AMR American, EAS East Asian, EUR European, SAS South Asian, NEM Northeast México, Ref reference value for studied population. A and C, G and C, C and T alleles

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