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Table 3 Frequency (percentage in parentheses) of allelic polymorphisms of CYP1A2 and CYP2E1 in pregnant women who were habitual caffeine consumers

From: Modulation of CYP2E1 metabolic activity in a cohort of confirmed caffeine ingesting pregnant women with preterm offspring

Genotype

Native

Heterozygous mutated

Homozygous mutated

CYP1A2*1F

rs762551

85 (100 %)

9 (10%)

A/A

30 (33%)

A/C

51 (57%)

C/C

CYP2E1*5A

rs3813867

87 (100%)

4 (5%)

G/G

21 (23%)

G/C

65 (72%)

C/C

CYP2E1*5B

rs2031920

87 (100%)

67 (75%)

C/C

18 (20%)

C/T

5 (5%)

T/T

  1. Note: A/A, A/C, C/C alleles of CYP1A2*1F; G/G, G/C, C/C alleles of CYP2E1*5A; C/C, C/T, TT alleles of CYP2E1*5B