Skip to main content
Molecular and Cellular Pediatrics
Fig. 3 | Molecular and Cellular Pediatrics

Fig. 3

From: Concepts for a therapeutic prolongation of nephrogenesis in preterm and low-birth-weight babies must correspond to structural-functional properties in the nephrogenic zone

Fig. 3

Transmission electron microscopy of a 1-day-old and glutaraldehyde-fixed rabbit kidney depicts mesenchymal cell projections (arrow) contacting epithelial cells and unveils extracellular matrix at the interface of the renal niche. a Specimens fixed by conventional glutaraldehyde (GA) solution illustrate a clear interface (asterisk). b In contrast, fixation by glutaraldehyde solution including cupromeronic blue (CMB) shows that numerous braces of proteoglycans are recognized on the surface of cell projections and within the basal lamina (arrow head) of epithelial stem cells. c Specimens fixed by GA solution including ruthenium red (RR) or d tannic acid (TA) unmasks further textured extracellular matrix at the interface and basal lamina of a CD ampulla, which is labeled by a cross

Back to article page