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Molecular and Cellular Pediatrics
Fig. 3 | Molecular and Cellular Pediatrics

Fig. 3

From: Neutrophil plasticity enables the development of pathological microenvironments: implications for cystic fibrosis airway disease

Fig. 3

Neutrophils as protagonists among contributors to CF airway disease. Neutrophils (center) establish metabolic and signaling ties with lung epithelial cells (bottom right) and resident planktonic and mucoid/biofilm bacteria (bottom left), while exerting primarily inhibitory control over other immune cells, including T cells and macrophages (top). The result of these complex relationships is the formation of a relatively stable pathological microenvironment within CF airways

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