Transient spontaneous remission in congenital MLL-AF10 rearranged acute myeloid leukemia presenting with cardiorespiratory failure and meconium ileus

Molecular and Cellular Pediatrics

Table 1 Results of molecular studies on MLL rearrangement

Sample type	Obtained at age	Method	Analysis	Result
Ileum biopsy	10 days	FISH	MLL rearrangement	Positive
Bone marrow	3 weeks	FISH	MLL rearrangement	Not feasible
Bone marrow	3 weeks	Nested PCR	MLL-AF10	Positive (in retrospect)
Bone marrow	5 weeks	FISH	MLL rearrangement	Negative
Bone marrow	5 weeks	Nested PCR	MLL-AF10	Positive (in retrospect)
Peripheral blood	5 months	FISH	MLL rearrangement	Positive
Peripheral blood	5 months	RT-PCR^a	MLL-AF10	Positive
Bone marrow	5 months	RT-PCR^a	MLL-AF10	Positive