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Molecular and Cellular Pediatrics
Fig. 1 | Molecular and Cellular Pediatrics

Fig. 1

From: Transient spontaneous remission in congenital MLL-AF10 rearranged acute myeloid leukemia presenting with cardiorespiratory failure and meconium ileus

Fig. 1

Submucosal infiltrate of polymorphic, atypical cells in the terminal ileum. Top row: ×25 magnification, bottom row: ×400 magnification. Left: hematoxylin and eosin (H&E) stain. Middle: KI67 staining shows a proliferation rate of 80 %. Right: the majority of cells display positive staining for the monocyctic marker CD68. A clonal MLL breakpoint in 11q23 was detected by FISH on paraffin embedded tissue-slides in the cells of the intestinal infiltrate. The population was classified as an extramedullary manifestation of monoblastic acute myeloid leukemia (AML FAB M5)

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