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Table 1 Potential causes of secondary or acquired sucrase-isomaltase deficiency or maldigestion

From: The clinical consequences of sucrase-isomaltase deficiency

Villous atrophy or alteration
 Celiac disease
 Non-tropical sprue
 Chemotherapy and radiation enteropathy
 Crohn’s disease
 Allergic enteropathy
 Acute gastroenteritis
 Tropical sprue
 HIV enteropathy
 Small intestinal bacterial overgrowth
Rapid transit
 Rapid gastric emptying
 Chronic nonspecific diarrhea
 Dumping syndrome
 Ulcerative, microscopic, and lymphocytic colitis