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Table 2 Expression of HRs in resident and nonresident cells of the skin

From: Expression and function of histamine and its receptors in atopic dermatitis

Cell type

Histamine receptor expression

Mast cells

H1R [10], H4R [116, 117]

Eosinophils

H1R [10], H2R, H3R [32, 91, 118, 119] H4R [120, 121]

Basophils

H4R [116, 117]

Neutrophils

H1R [10], H2R [122, 123], H4R [116, 117]

Dendritic cells

H1R [34], H2R [34], H3R [32, 19, 118, 119], H4R [33]

Langerhans cells

H4R [35]

Monocytes/macrophages

H1R [10], H2R [122, 123], H3R [32, 91, 118, 119], H4R [8]

T cells

H1R [10], H2R [122, 123], H4R [100, 117, 124]

B cells

H1R [10], H2R [122, 123]

Keratinocytes

H1R [10], H2R [71]

Endothelial cells

H1R [10], H2R [122, 123], H1R–H4R [74]

Smooth muscle cells

H1R [10], H2R [122, 123]

Fibroblasts

H1R [82]

Neurons

H1R [10], H2R [122, 123], H3R [32, 91, 118, 119]