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Molecular and Cellular Pediatrics
Figure 1 | Molecular and Cellular Pediatrics

Figure 1

From: Propofol administration to the maternal-fetal unit improved fetal EEG and influenced cerebral apoptotic pathway in preterm lambs suffering from severe asphyxia

Figure 1

Study design and time course of experiments. Lambs were born at 89% of gestation. The ewes carrying the gestational age control group were euthanized and their offspring was delivered by cesarean section and subsequently euthanized. The ewes of the other groups underwent the cesarean section while being sedated with the same anesthetic as their offspring later on intensive care unit. Two groups were exposed to an average time of total umbilical cord occlusion (UCO) of 11 min. The cutoff for the occlusion was a MABP below 30 mmHg for exactly 2 min. This protocol always led to severe bradycardia (HR < 30/min) or even cardiac arrest.

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