Table 1 Patient demographics of the FMF cohorts and healthy controls

Gender (female/male)

9/9

10/9

21/18

8/11

Mutations

M694V/M694V

n/a

M694V/M694V

M694V

Age in years at diagnosis (median, 25th–75th percentile)

4.9 (3.4–10.9)

n/a

5.3 (3.2–7.6)

5.6 (3.6–12.0)

Medication

Colchicine

n/a

Colchicine

Colchicine

CRP (mg/dl)

<0.5

<0.5

<0.5

<0.5

SAA (mg/l)

9.9 (6.5–12.2)

8 from 18 neg.

5.7 (5.2–7.6)

16 from 19 neg.

3 (2–5)

2 (1–4)

ESR (mm/h)

9 (6–14)

5 (3–6)

12 (8–15)

8 (5–13)

Leukocytes (per nl)

7.7 (5.8–8.5)

6.5 (5.5–7.7)

7.2 (6.2–8.65)

6.850 (5.1–9.6)

S10012 (ng/ml)

n/a

n/a

170 (80–280)

81 (43–101)

S100A8/A9 (ng/ml)

15,730 (8975–18,730)

2040 (1400–3820)

11,225 (3896–28,627)

3938 (1650–6703)